Mark Twain Brewing Company

Brewpub in Hannibal, Missouri

Contact & Location

📍 422 N Main St, Hannibal, Missouri, 63401-3324

Listing data comes from Open Brewery DB (imported November 2025). Breweries open, move and close often, so confirm hours before you go.

Type: Brewpub

City: Hannibal

State/Region: Missouri

Country: United States

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